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Compugen ltd bags cancer deal worth 540 million Get the latest biotech news where you Cheap Louis Vuitton Bags want it.Sign up for the today! Compugen announces collaboration and license agreement with bayer http://www.austherm.com.au/ for antibodybased cancer immunotherapies Tel aviv, israel(Business wire) (Nasdaq:Cgen)Announced today the signing of a collaboration and license agreement for the research, development, and commercialization of antibodybased therapeutics for cancer immunotherapy against two novel compugen discovered immune checkpoint regulators.Under the terms of the agreement, Bayer healthcare(Bayer)And compugen will jointly pursue a preclinical research program.Subsequently, bayer will have full control over further development and have worldwide commercialization rights for potential cancer therapeutics. Under the agreement compugen will receive an upfront payment of usd 10 million, and is eligible to receive over usd 500 http://www.austherm.com.au/ million in potential milestone payments for both programs, not including milestone payments of up to usd 30 million associated with preclinical activities.Additionally, compugen is also eligible to receive mid to high single digit royalties on global net sales of any resulting products under the collaboration. "Bayer is committed to translating the science of cancer research into effective therapies helping people affected by cancer live longer and improve their quality of life,"Said prof.Andreas busch, member of the bayer healthcare executive committee and head of global drug discovery. "Antibodybased immunotherapies are promising approaches in oncology which can stimulate the body's own immune cells to fight cancer cells.Immunotherapy is one of our focus areas in oncology research.In addition, we believe that the prediction and validation of these two targets, through the use of our broadly applicable predictive discovery infrastructure, provides additional validation for our longterm commitment to establishing this unique capability". The immunotherapy approach aims at combatting cancer by stimulating the body's own immune cells.The tumor and its environment suppress the ability of cancer patients to develop an effective antitumor immune response and in this way protect both tumor growth and survival.Compugen has discovered two novel immune checkpoint regulators that potentially play a key role in immunosuppression.Researchers at compugen are developing specific therapeutic antibodies that are geared to block the immunosuppressive function of these targets and to reactivate the patient's antitumor immune response in order to fight cancer. Latest cancer immunotherapies have demonstrated impressive clinical benefit, even for endstage patients with difficulttotreat tumors such as metastatic melanoma and nonsmall cell lung cancer.Unlike conventional cancer therapies, which act by directly targeting the cancer cells, resulting often in only transient clinical responses as cancer cells become resistant, clinical responses to cancer immunotherapy tend to be durable, sometimes resulting in dramatic long term survival and absence of resistance or recurrences. Compugen is a leading drug discovery company focused on therapeutic proteins and monoclonal antibodies to address important unmet needs in the fields of immunology and oncology.The company utilizes a broad and continuously growing integrated infrastructure of proprietary scientific understandings and predictive platforms, algorithms, machine learning systems and other computational biology capabilities for the in silico(By computer)Prediction and selection of product candidates, which are then advanced in its pipeline program.The company's business model includes collaborations covering the further development and commercialization of selected product candidates from its pipeline program and various forms of research and discovery agreements, in both cases providing compugen with potential milestone payments and royalties on product sales or other forms of revenue sharing.In 2012, compugen established operations in california for the development of oncology and immunology monoclonal antibody therapeutic candidates against compugen drug targets. On august 2, 2013 compugen filed form6k with its financial statements for the six months ended june 30, 2013 and will host a public conference call at 10:00 AM ET on Wednesday, August 7, 2013 to discuss these results and any questions with respect to this press release.Further information regarding the conference call is provided in a separate press release issued today and on our website. The bayer group is a global enterprise with core competencies in the fields of health care, agriculture and hightech materials.Bayer healthcare, a subgroup of bayer ag with annual sales of eur 18.6 billion(2012), is one of the world's leading, innovative companies in the healthcare and medical products industry and is based in Leverkusen, Germany.The company combines the global activities of the animal health, consumer care, medical care and pharmaceuticals divisions.Bayer healthcare's aim is to discover, develop, manufacture and market products that will improve human and animal health worldwide.Bayer healthcare has a global workforce of 55, 300 employees(Dec 31, 2012)And is represented in more than 100 countries. This press release contains"Forwardlooking statements"Within the meaning of the private securities litigation reform act of 1995.These statements, which include statements related to the potential developmentAndcommercialization of antibodybased cancer immunotherapies against the compugendiscovered immune checkpoint targets, potential milestoneAndroyalty payments,Andthat the collaboration validates Louis Vuitton Mens compugen's predictive discovery infrastructure, include words such as"May," "Expects," "Anticipates," "Potential," "Believes,"And"Intends,"Anddescribe opinions about future events. These Forwardlooking statements involve knownAndunknown risksAnduncertainties that may cause the actual results, performance or achievements of Compugen to be materially different from any future results, performance or achievements expressed or implied by such Forwardlooking statements. Some of these risksAndother factors are discussed in the "Risk factors" section of Compugen's Annual Report on Form 20F for the year ended December 31, 2012 as filed with the SecuritiesAndExchange Commission. In addition, any Forwardlooking statements represent Compugen's views only as of the date of this releaseAndshould not be relied upon as representing its views as of any subsequent date.Compugen does not assume any obligation to update any forwardlooking statements unless required by law.

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